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Synthesis and Medical Application of 3D Graphene Materials Figure 20. Typical Structure of Poly-l-lactic Acid Figure 21. Typical Structure of a Bone (Ambekar & Kandasubramanian, 2019) As Sensors for Magnetic Resonance Imaging (MRI) Scanning Graphene has found applications as sensors for medical Magnetic Resonance Imaging (MRI) due to its unique properties. Piezoelectric sensors constructed from Poly (Vinylidene fluoride) PVDF, or a similar polymer connected by metallic thin films were used as early as 1992, but this sensor proved to be inefficient as metals have a high susceptibility to distortion and inhomogeneity to the magnetic field and caused further distortion of the image and lead to misdiagnosis and even mimic of the disease. Graphene posed a combination of high conductivity and extreme strain resilience in contrast with many other metallic and organic thin films, it is also a nontoxic, air- stable material that provides the minimum contribution to device stiffness of profile. Furthermore, it is more situated for MRI use because carbon 12 (the predominant isotope of carbon) has no net spin and is consequently not detected. Its negligible volume also minimizes distortion of the magnetic field. Large area Chemical Vapor Deposition (CVD) grown monolayer graphene films were shown to be an outstanding electrode material for replacing the traditional metallic conductors in piezoelectric respiratory monitors, this was carried out in vivo and clearer images with minimal distortion for the MRI scan as see in the data obtained from a graphene-based sensor (GRS), featuring a comparison of the typical trace of the pulsed breathing of a sedated mouse measured using a respiratory balloon or metal contacted piezoelectric sensors showed shorter signal decay time and visible heartbeat from the graphene transducer (Figure 22a) and also a plot of the trigger and gating signals generated from the respiratory signal proved the efficiency of the use of the graphene material over other sensors as reported (Tweedie et al., 2020). 2536|Indonesian Journal of Multidisciplinary Science, 2(5), Feb, 2023PDF Image | Medical Application of 3D Graphene
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