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Dovepress Formation of curcumin nanoparticles by the seDs process × × × × × × × × × Figure 3 seM micrographs of curcumin nanoparticles prepared by the seDs process under different conditions (A) 0.5%-35°c-0.5 ml/min-20 Mpa; (B) 0.5%-45°c-1 ml/min-10 Mpa; (C) 0.5%-45°c-0.5 ml/min-10 Mpa; (D) 5%-45°c-0.5 ml/min-20 Mpa; (E) 0.5%-35°c-1 ml/min-10 Mpa; (F) 1%-45°c-0.5 ml/min-20 Mpa; (G) 1%-45°c-1 ml/min-20 Mpa; (H) 1%-35°c-1 ml/min-20 Mpa; (I) 0.5%-35°c-1 ml/min-20 Mpa. Abbreviations: seM, scanning electron microscopy; seDs, solution-enhanced dispersion by supercritical carbon dioxide (cO2). Figure 4 standardized effect of the factors on particle size. International Journal of Nanomedicine 2015:10 ° ) Powered by TCPDF (www.tcpdf.org) submit your manuscript | www.dovepress.com Dovepress 3175 International Journal of Nanomedicine downloaded from https://www.dovepress.com/ by 158.132.161.240 on 23-Nov-2018 For personal use only.PDF Image | curcumin nanoparticles via solution supercritical cO2
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