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EXECUTIVE SUMMARY 14 MARKET IMPACTS OF CONVERTING TO LOW-ENRICHED URANIUM TARGETS FOR MEDICAL ISOTOPE PRODUCTION, ISBN 978-92-64-99197-2, © OECD 2012 option of purchasing or producing HEU-based 99Mo and/or 99mTc less attractive; or limiting access to HEU-based 99Mo/99mTc. While countries may have differing views on the various options, given their own economic, regulatory, or political situation, the discussion paper provides a brief review of the options from the starting point of the HLG-MR policy approach to achieving a long- term reliable supply of 99Mo/99mTc. Conclusion The NEA study, developed in collaboration with experts from the supply chain and with the HLG-MR, demonstrates the expected capacity and cost impacts of converting to using LEU targets for the production of 99Mo. The findings show that LEU-target conversion will have an impact on capacity, but will not be the major factor that causes long-term shortages. The main concern is the continued economic situation in the 99Mo/99mTc supply chain that is unsustainable for any investment, including LEU-based investment. As a result, achieving full-cost recovery pricing is a necessary (but insufficient) condition for ensuring long-term supply reliability and allowing LEU-target conversion. LEU-target conversion does have important impacts on the availability of outage reserve capacity – in the long term for irradiation capacity, but only affecting processing capacity during the conversion period. In addition, it is clear that 99Mo/99mTc produced from converted facilities is more expensive that HEU-based 99Mo. However, the increase at the radiopharmacy stage is less than 8%. This small impact on the end payer translates to an important increase upstream and the end payer will need to accommodate the increase to ensure sufficient funding for the investment required upstream in the supply chain. Evidence from the study points to an important role for governments to encourage LEU-target conversion, to help to ensure the long-term secure supply of these important medical isotopes.PDF Image | Market Impacts of Converting to Low-enriched Uranium Targets for Medical Isotope Production
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