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NASA Engages with Emerging Space: Economic Development and the ISS The ISS is the most complex international scientific and engineering project in history and the largest structure humans have operated in space. It is also the core of our human economy in space with six people living within it. The ISS is a partnership between the United States, Russia, Europe, Japan, and Canada, with 15 nations coming together to design, assemble, occupy, and conduct research inside and out. For the last 10 years, research has been primarily conducted by the government and public sector. For the next decade, NASA is actively welcoming a broader array of partners and is pursuing the continued economic development of our home in orbit. NASA seeks and encourages the utilization of the ISS for scientific research by commercial firms, universities, non- profits, and other organizations, offering access to its high-quality microgravity facility for research in life and physical sciences. The microgravity environment holds promise for private-sector research in pharmaceuticals, biotechnology, physical sciences, and life sciences, as it allows cells and crystals to grow larger, and alloys and materials to form with fewer impurities, than they can under gravity. The ISS was designated a National Laboratory in 2005, and NASA helped create the Center for Advancement of Science in Space (CASIS) to manage the use of the station for scientific research. The ISS is also our first international human economic ecosystem in space and we are learning how to foster economic development in space through its utilization and further development. NASA uses ISS to collaborate with businesses in three ways: Healthcare company Merck started conducting crystallization research on therapeutic monoclonal antibodies designed to cure immunological diseases. Microgravity facilitates pure crystal growth, which in turn can produce more effective drugs. The J. Craig Venter Institute is analyzing how the composition of the human microbiome changes during long-term space exploration, evaluating its potential impact on astronaut health. The institute is also investigating microbe filters, to characterize the enormous diversity of microbes that are normally present in indoor environments. Biotechnology firm Amgen conducted bone loss experiments aboard ISS in 2011. Bone loss is a serious concern for astronauts in microgravity as well as millions of women on Earth. The research is expected to inform mitigation strategies in both cases. 5PDF Image | Emerging Space
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