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S124 P. MATHUR ET AL. by silver nanoparticles at various degrees leads to their pitfall. It is suggested that higher concentrations of silver nanopar- ticles are toxic and can cause various health problems and can induce various ecological problems if released into the environment. Varied applications of silver nanoparticles is found in the form of wound dressings, coatings for medical devices, silver nanoparticles impregnated textile fabrics, etc., as there is uninterrupted release of silver ions and the devi- ces can be coated by both the outer and inner side hence, alleviating its antimicrobial efficacy. However, there are some issues, which need to be addressed, such as, the exact mechanism of interaction of sil- ver nanoparticles with the bacterial cells, how the surface area of nanoparticles influence its killing activity, use of ani- mal models and clinical studies to get a better understanding of the antimicrobial efficiency of silver dressings, the toxicity if any of the silver dressings, etc. Hence, care has to be taken to utilize this marvel well and in a good, effective and effi- cient way, understanding its shortcoming and taking utmost care that it does not cause any harm to an individual or the environment. On the whole, the silver nanoparticles due to their unique properties of silver and nano size appear to be promising in pharmaceutical, biomedical and allied fields provided safety data is generated to prove their safety and simultaneously ruling out their toxicity. Disclosure statement No potential conflict of interest was reported by the authors. 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