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Nanomaterials 2020, 10, 376 11 of 22 3.1.2. Thermal Stability The thermal stability of GO and GO–AgNP nanohybrids was measured by TGA under a nitrogen atmosphere. For GO and all GO–AgNP nanohybrids, the TGA mass loss curves display Nanomaterials 2020, 10, x FOR PEER REVIEW 11 of 22 two decomposition steps (Figure 5). The first mass loss, attributed to the elimination of interlaminar water, is found at 50−120 ◦C, and the second, where the decomposition of the oxygen groups occurs, at water, is found at 50−120 °C, and the second, where the decomposition of the oxygen groups occurs, 140–300 ◦C. During this step, the largest mass loss corresponds to GO (~32%), and decreases as the at 140–300 °C. During this step, the largest mass loss corresponds to GO (∼32%), and decreases as the concentration of AgNO3 and temperature increase, being 16.1, 7.7, 12.2, and 5.4% for GO–AgNP-A, concentration of AgNO3 and temperature increase, being 16.1, 7.7, 12.2, and 5.4% for GO–AgNP-A, GO–AgNP-B, GO–AgNP-C, and GO–AgNP-D, respectively. From these results, it can be concluded GO–AgNP-B, GO–AgNP-C, and GO–AgNP-D, respectively. From these results, it can be concluded that the most stable hybrid is the one obtained at the highest silver precursor concentration and the that the most stable hybrid is the one obtained at the highest silver precursor concentration and the highest temperature. The improvement in the thermal stability is attributed to the deoxygenation and highest temperature. The improvement in the thermal stability is attributed to the deoxygenation and better graphitization of the hybrids because of the partial reduction of GO. better graphitization of the hybrids because of the partial reduction of GO. 3.1.3. Antimicrobial Activity Assessment 3.1.3. Antimicrobial Activity Assessment Figure 5. TGA curves of GO and GO–AgNP nanohybrids. Figure 5. TGA curves of GO and GO–AgNP nanohybrids. Healthcare-associated infectious diseases are a relevant medical problem because they prolong Healthcare-associated infectious diseases are a relevant medical problem because they prolong hospital stay and cause long-term disability and additional costs for health systems, patients and their hospital stay and cause long-term disability and additional costs for health systems, patients and families, and preventable deaths. Moreover, treatment of these diseases increases the possibility of their families, and preventable deaths. Moreover, treatment of these diseases increases the possibility osfelseeclteinctginmgumltiu-dltriu-dgrruegsisrteasnisttmanictrmooircgroanorisgmans.isTmhse.mTohsetmfreoqsutefnretqeutieonlotgeictiaollaogeicnatlsargeGntrsamar-eneGgratmiv-e n(Eeg.caotliivaen(dE.P.caoeliruagnidnoPsa.)aenrudgGinroasma)-paonsditiGvrea(mS.-pauorseiutisv)eba(Sc.tearuiareaunsd) byaecatsetrsia(Ca.nadlbiycaenas)ts[4(3C,4.4a]l.biTchanes)e [f4o3u,4r4m].iTcrhoeosregfaonuirsmsicwroeorregsaenleiscmtesdwineroerdselretcoteudnidneorrsdtaenrdtothuenbdehrsatvainodrothfeGbOe–hAavgiNorPonfaGnOoh–AybgrNidPs noanndoihffyebrerindtsmoincrdoibffiearlesntrtumctiucroesbisaulcshtrauscGturaems s-puochsitaisveGarnamd G-proasmiti-vnegaantdivGe rbamct-enreiagatsivweebllaacsteyreiasats. wTheellseasinyfeactsitosu.sTahgeesnetisnafreectiroaunsmagitetendtsmaareintlryabnysmcointtteadctmwaitihnlpyeboyplceownhtaocctawrriythorpaeroepilnefewctheodcbayrrthyeomr, arsewinelfleactsetdhrboyugtheombj,ecats(wfoemllitaess)t,hfrooudg,hwaotbejre,catnsd(faonmimiteasls),.Afololdfo,uwramteicr,roaonrdgaannisimsalcsa.nAblelcfomure mpaicrtroofrtghaenhiusmsancamnibcerocobmioteapaanrdt ocfanthseuhbusemqaunenmtliycrcoabuisoetaopanpdorctaunisutibcsienqfeucetniotlnys.caEupsiedeomppicosrtruaninistiocf itnhfescetisopnesc.iEesphidaevme aiclsotrbaeinens odfetshcreisbeesdptehcaiet scahuasveemalosdoebreaetenadnedscsreivberde tihnafetctaiounsse imn opdeoerpalteewanitdhosuetvaenrey iunnfedcetriolynisngindipseaospeleorwimitmhouuntoadneyficuiendceyr[l4y5in].gTdhiesseaspeeociresimarmeaumnodnegftihciemncoyst[f4r5e]q.uTehnetsaendspimecpieosrtarnet acmauosnegsothfehmeaoltshtcfarreeq-uasesnotcaiantdediminpfoecrtiaonutscdauisseeaseosf.hTehaeltyhcaarerea-lassosopcrioabtleedminatfieccstipoeucsiedsidseuaesetos.rTeshiesytaanrce aolrsompurlotib-lremsisataicncsepetocieasntdibuieotoicsr.esGisrtamnc-eposritmivueltSi-.raeusrisetuasnicseatomanjotirbhioutmicsa.nGpratmho-pgoesnittihvaetSc.aausresusa iwsiademraajonrgehuomfcalninipcatlhiongfecntitohnast.cIatuiseaslaeawdindgecranugseofbcalicntiecraelminiafeacntidonosn.eItoifsthaelemadoisntgimcapuosretaonft bcacutseersemofiadeaantdhoansseoocfiathteedmwoistht ibmlopodrtsatnretacmauisnefsecotfiodnea[t4h6]a.sAsonctiiabtieodtiwc riethsibstlaonocdestisrecaomimnfoenc,tiwonith[4t6h]e. Amnotsibtiportoicbleremsiastiacnscterainsscboeminmgothno,sweictahlletdheMmRSoAst(pmreotbhliecmillainti-crestirsatainstSb.eaiunrgeutsh).osGeracmal-lnedegaMtiRvSeAE. (methicillin-resistant S. aureus). Gram-negative E. coli is a major cause of bloodstream infection, as well as the most common pathogen causing urinary tract infection and catheter-associated urinary tract infections, and a critical antimicrobial resistance issue [47]. Multidrug resistance is common in E. coli: Among the most frequent mechanisms are the production of beta-lactamases and modifications of antibiotic targets. Gram-negative P. aeruginosa is the main cause of ventilated- associated pneumonia in the intensive care unit and a common cause of other nosocomial infectionsPDF Image | Graphene Oxide–Silver Nanoparticle Nanohybrids
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