PDF Publication Title:
Text from PDF Page: 009
Molecules 2020, 23, x FOR PEER REVIEW 9 of 36 as the nanocarrier, enhanced the cellular uptake and ROS scavenging ability than single drug loading Molecules 2020, 25, 4613 9 of 36 [164]. Figure 3.. Liposome structure and drug loading diagram: (A) Cross-section structure of liposome, made of phospholipid and cholesterol, showing the magnifified molecular structure of a phospholipid thatconsistsofapollarheadandanon--pollarrttaiill..Phospholipidheadiishydrophobicandcomprises choline, phosphate and glycerol, while the tail is a hydrocarbon chain that shows lipophilicity. (B) A choline, phosphate and glycerol, while the tail is a hydrocarbon chain that shows lipophilicity. (B) A schematic representation of the structure and preparation of phytosomal curcumin. Reprinted from schematic representation of the structure and preparation of phytosomal curcumin. Reprinted from reference [134,159]. Copyright 2016 Elsevier Masson SAS, 2019 Elsevier Ltd. reference [134,159]. Copyright 2016 Elsevier Masson SAS, 2019 Elsevier Ltd. However, the limitation of liposome is that it has a short half-life and can be easily oxidized and However, the limitation of liposome is that it has a short half-life and can be easily oxidized and hydrolyzed. It was previously reported that the intravenous administration of resveratrol resulted in hydrolyzed. It was previously reported that the intravenous administration of resveratrol resulted in a short t1/2, ranging from 7.8 to 33 min [165]. Therefore, many modified liposomes came into being. a short t1/2, ranging from 7.8 to 33 min [165]. Therefore, many modified liposomes came into being. In In order to increase the half-life and extend the blood circulation time, Caddeo et al. [166] grafted order to increase the half-life and extend the blood circulation time, Caddeo et al. [166] grafted polyethylene glycol chains (PEGylated liposomes) at the ends of liposomes to deliver resveratrol. polyethylene glycol chains (PEGylated liposomes) at the ends of liposomes to deliver resveratrol. Drug release results indicated that the half-life of polyethylene glycol modified liposomes was increased Drug release results indicated that the half-life of polyethylene glycol modified liposomes was by about nine times, while the inherent antioxidant activity was still maintained. By mixing with increased by about nine times, while the inherent antioxidant activity was still maintained. By mixing various biopolymers, the storage stability of liposomes was improved [167]. The biopolymers include with various biopolymers, the storage stability of liposomes was improved [167]. The biopolymers anionic (such as arabinose and whey protein) and cationic (such as chitosan). It was also proven that include anionic (such as arabinose and whey protein) and cationic (such as chitosan). It was also the encapsulation rate of polyphenols in liposomes and their antioxidant activity will increase with the proven that the encapsulation rate of polyphenols in liposomes and their antioxidant activity will addition of biopolymers. increase with the addition of biopolymers. 3.2.2. Solid Lipid Nanoparticles (SLNs) 3.2.2. Solid Lipid Nanoparticles (SLNs) Solid lipid nanoparticle is a solid colloidal drug delivery system which is made by wrapping Solid lipid nanoparticle is a solid colloidal drug delivery system which is made by wrapping or or inserting drugs in lipid nucleus with natural or synthetic lipids, such as lecithin and triglyceride. inserting drugs in lipid nucleus with natural or synthetic lipids, such as lecithin and triglyceride. The The emergence and development of SLNs successfully make up for the limitations of traditional emergence and development of SLNs successfully make up for the limitations of traditional nanocarriers (such as nanoemulsion and liposomes), with advantages including controlling drug release nanocarriers (such as nanoemulsion and liposomes), with advantages including controlling drug and targeting, increasing drug stability, high drug loading, low toxicity, and loading of hydrophilic release and targeting, increasing drug stability, high drug loading, low toxicity, and loading of lipophilic drugs. hydrophilic lipophilic drugs.PDF Image | Nanoformulations to Enhance the Bioavailability and Physiological Functions of Polyphenols
PDF Search Title:
Nanoformulations to Enhance the Bioavailability and Physiological Functions of PolyphenolsOriginal File Name Searched:
molecules-25-04613-v2.pdfDIY PDF Search: Google It | Yahoo | Bing
Turbine and System Plans CAD CAM: Special for this month, any plans are $10,000 for complete Cad/Cam blueprints. License is for one build. Try before you buy a production license. More Info
Waste Heat Power Technology: Organic Rankine Cycle uses waste heat to make electricity, shaft horsepower and cooling. More Info
All Turbine and System Products: Infinity Turbine ORD systems, turbine generator sets, build plans and more to use your waste heat from 30C to 100C. More Info
CO2 Phase Change Demonstrator: CO2 goes supercritical at 30 C. This is a experimental platform which you can use to demonstrate phase change with low heat. Includes integration area for small CO2 turbine, static generator, and more. This can also be used for a GTL Gas to Liquids experimental platform. More Info
Introducing the Infinity Turbine Products Infinity Turbine develops and builds systems for making power from waste heat. It also is working on innovative strategies for storing, making, and deploying energy. More Info
Need Strategy? Use our Consulting and analyst services Infinity Turbine LLC is pleased to announce its consulting and analyst services. We have worked in the renewable energy industry as a researcher, developing sales and markets, along with may inventions and innovations. More Info
Made in USA with Global Energy Millennial Web Engine These pages were made with the Global Energy Web PDF Engine using Filemaker (Claris) software.
Infinity Turbine Developing Spinning Disc Reactor SDR or Spinning Disc Reactors reduce processing time for liquid production of Silver Nanoparticles.
| CONTACT TEL: 608-238-6001 Email: greg@infinityturbine.com | RSS | AMP |