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Nanomaterials 2020, 10, 979 11 of 16 Finally, the International Cooperation on Cosmetics Regulation (ICCR), established in 2007 [84], is an international group of cosmetics regulatory authorities from Brazil, Canada, the EU, Japan, and the USA, which meets on an annual basis to address common issues on cosmetics safety and regulation, including the use of NMs in cosmetics. The ICCR provides a multilateral framework to maintain global consumer protection, by working towards regulatory convergence. 5. Perspectives/Outlook Nanomaterials can be used in cosmetic industry in various forms and types. It is a fact that due to the progress and development of R&D in the cosmetic industries, an increasingly large number of nanostructures are tested in cosmetics. The future target is clear: to find the safest and most appropriate nanomaterial to use in multiple cosmetic applications but with the lowest cost. Also, it is mandatory to mention that “EU is to promote the development and validation of alternative methods that adhere to the 3Rs principle, and to provide a level of safety equivalent to that obtained through animal testing while using fewer animals, causing less suffering, or avoiding any use of animals. In view of the ban, the need for implementing non-animal alternatives is particularly crucial for safety assessment of cosmetic ingredients/products because safety data can only be drawn from alternative methods, meaning that the 3Rs choices are effectively restricted to 1R (i.e., Replacement of animal testing). In view of this, the SCCS considers all available scientific data, taking into account the testing and marketing bans in force under Regulation (EC) No 1223/2009”. The latter statements are the first major target to follow, because the variety of nanomaterials in cosmetic is tremendous, but the ethics must be kept intact. The future will show what the major future trends and needs in the nanocosmetics sections will be [85]. Sustained and controlled release of sunscreens, with improved moisturizing capacity along with anti-aging properties could potentially be established. Some very promising delivery systems are being investigated, with an array of practical applications. While some may not find their way out of the laboratories, others have the potential to bring major breakthroughs in the cosmetic world. An exceptionally unique nanomaterial, carbon nanobuds have been identified with the combined properties of carbon nanotubes and fullerenes. They are prepared by combining the two most common allotropes of carbon, fullerenes, and carbon nanotubes. Carbon nanotubes are specifically covalently bounded to fullerene-like “sprouts/buds”. They possess remarkably good field emitting properties. This may be of particular use in the manufacture of lipsticks and mascaras. Furthermore, new nanosized metal pigments, in addition to the widely known titanium dioxide and zinc oxide, should be continuously investigated and proposed for cosmetics. In addition, specifically shaped nanoparticles made to fill the uneven surfaces—especially after plastic surgery—for aesthetic appearance of body parts, may open new horizons. Another promising area could be the triggered release of nanomaterials on the skin facilitated by skin pH gradient. Enzymes conjugated with protein nano-carriers have also been receiving attention, due to their exceptional water binding capacity into the stratum corneum. The number of patent applications registered in the last five years suggests that there could be an increased activity in the protein conjugation area in the immediate years ahead. Despite the plethora of benefits nanocosmetics may bring one cannot deny the potential dangers that are linked to some nanomaterials. Furthermore, risk estimation of nanomaterials ought to be carried out on an item-by-item basis, using relevant information. If the presented cosmetic nanomaterial development is allowed to bloom after the currently ongoing nanotoxicity and safety research incentives have had a chance to affect regulations and guidelines for production and use of nanomaterials, and if the necessary commercial support is in place to carry the materials presented in recently published scientific articles and granted patents to the market, we can soon expect to see a range of new nanotechnology-based cosmetic products on the shelves of the nearest drug store [2]. These include new sunscreens containing diamond nanoparticles attenuating UV radiation while simultaneously removing the free radicals generated by UV light, long-lasting hair dyes with carbon nanotubes providing smoothening, volumizing, and anti-damaging effects, dental-care products containing fluoride nanoparticles treating dentinPDF Image | Nanomaterials in Cosmetics: Recent Updates
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