PDF Publication Title:
Text from PDF Page: 007
Nanomaterials 2019, 9, 1629 7 of 21 the transmucosal delivery of tea catechins. According to the same authors, nanoencapsulated catechins could be used as food additives and dietary supplements. It has been found that, among tea polyphenols, EGCG has the largest scavenging capacity [99,100], but in many studies, it has been indicated that EGCG has low bioavailability because of its large-sized molecules and the number of hydrogen bonds [100,101]. Application of chitosan/β-lactoglobulin nanocarriers provided sustained release of tea EGCG and thereby increased its absorption in the human intestine [45]. Nanocarriers such as dextran sulfate, combined with N,N-dimethylhexadecyl carboxymethyl chitosan nanoliposome (DS-DCMC-NL), are also a suitable carrier for EGCG, which possesses a high encapsulation capacity and the potential for further application in food processing [102]. In addition to tea-polyphenol-loaded nanoparticles, there are studies that examined the nanoencapsulation of other polyphenol nutrients that exert antioxidant activity, such as curcumin [5,43,51,52], quercetin [58–60], rutin [49], and naringenin [2,62]. According to Chang et al. [52], the use of pectin-coated NaCas/zein nanocarriers for curcumin encapsulation significantly improved its antioxidant activity and prolonged its release capabilities in simulated gastric and intestinal fluids, whereas quercetin-loaded solid-lipid nanoparticles improved its bioavailability [60]. The determination of the antioxidant properties of polyphenol-loaded nanoparticles was done using different antioxidant assays, such as ABTS/DPPH radical scavenging activity, hypochlorous acid/hydrogen peroxide scavenging assays, and ferric-reducing ability (Table 2). Table 2. Methods used for determination of the biological properties of polyphenol-loaded nanoparticles. Antioxidant/Cytotoxic (Cell line/Animal Model) Assays ABTS radical scavenging activity DPPH radical scavenging activity Hypochlorous acid (HOCl) scavenging assay Ferric-reducing ability (FRP) Hydrogen peroxide scavenging assay TEER measurements and transport studies (Caco-2 cell) Cell viability (Hepatocellular carcinoma cells SMMC7721 and hepatocyte LO2 cells) Monkey kidney (Vero) cell lines-sulforhodamine B assay Antitumor effect in vitro assays (CT26 mouse colon cancer cells) In vitro cell culture study (Cochlear cell lines (HEI-OC1 and SVK-1) In vitro hemolytic/anticancer assay (human cancer cell lines i.e., leukemia cancer (HL60), oral cancer (SCC40), breast cancer (MCF7), cervix cancer (HeLa) and colon cancer (Colo205)- sulforhodamine B assay) In vitro cytotoxicity assay (SK-MEL-28 and Colo-38 cells) In vitro assays in cells from different origin (cultivated HepG2 cells, isolated primary rat hepatocytes, isolated murine spleen lymphocytes and macrophages) In vitro cytotoxicity assay (Human hepatoma HepG2 cells) In vitro assay (human hepatoblastoma cancer cell line HepG2) Active Compounds Curcumin Tea polyphenols Catechin Curcumin Resveratrol Resveratrol/quercetin Resveratrol Resveratrol/quercetin Tea polyphenols Catechin Resveratrol Resveratrol/quercetin Resveratrol Catechin Resveratrol Resveratrol Resveratrol Resveratrol EGCG/EGCG + piperine Resveratrol Quercetin Tea polyphenols (TP) Tea polyphenols Nanocarrier Pectin-coated sodium caseinate/zein NPs Lysozyme-carboxymethyl cellulose nanogels Chitosan/poly-γ-glutamic acid NPs Caseinate-zein-polysaccharide nanocomplex Chitosan-TPP (sodium tripolyphosphate) NPs Chitosan NPs/polyethylene glycol modified chitosan NPs PLGA [poly(lactic-co-glycolic acid)] -oil hybrid NPs Liposome Lysozyme-carboxymethyl cellulose nanogels Chitosan/poly-γ-glutamic acid NPs Bovine serum albumin-based NPs Chitosan NPs/polyethylene glycol modified chitosan NPs PLGA [poly(lactic-co-glycolic acid)] -oil hybrid NPs Chitosan/poly-γ-glutamic acid NPs Chitosan-TPP (sodium tripolyphosphate) NPs PLGA [poly(lactic-co-glycolic acid)] -oil hybrid NPs Polyethylene glycol-polylactic acid polymer NPs Polymeric NPs Zein Ultradeformable liposomes Chitosan/alginate NPs CS NPs (using carboxymethyl chitosan and chitosan hydrochloride) Lysozyme-carboxymethyl cellulose nanogels Reference Chang et al. [52] Liu et al. [103] Tang et al. [54] Chang et al. [43] Wu et al. [104] Natesan et al. [105] Kumar et al. [106] Caddeo et al. [107] Liu et al. [103] Tang et al. [54] Fonseca et al. [108] Natesan et al. [105] Kumar et al. [106] Tang et al. [54] Wu et al. [104] Kumar et al. [106] Jung et al. [109] Musazzi et al. [110] Dahiya et al. [71] Cosco et al. [111] Aluani et al. [58] Liang et al. [57] Liu et al. [103]PDF Image | Polyphenol-Loaded Nanoparticles in Food Industry
PDF Search Title:
Polyphenol-Loaded Nanoparticles in Food IndustryOriginal File Name Searched:
nanomaterials-09-01629.pdfDIY PDF Search: Google It | Yahoo | Bing
Turbine and System Plans CAD CAM: Special for this month, any plans are $10,000 for complete Cad/Cam blueprints. License is for one build. Try before you buy a production license. More Info
Waste Heat Power Technology: Organic Rankine Cycle uses waste heat to make electricity, shaft horsepower and cooling. More Info
All Turbine and System Products: Infinity Turbine ORD systems, turbine generator sets, build plans and more to use your waste heat from 30C to 100C. More Info
CO2 Phase Change Demonstrator: CO2 goes supercritical at 30 C. This is a experimental platform which you can use to demonstrate phase change with low heat. Includes integration area for small CO2 turbine, static generator, and more. This can also be used for a GTL Gas to Liquids experimental platform. More Info
Introducing the Infinity Turbine Products Infinity Turbine develops and builds systems for making power from waste heat. It also is working on innovative strategies for storing, making, and deploying energy. More Info
Need Strategy? Use our Consulting and analyst services Infinity Turbine LLC is pleased to announce its consulting and analyst services. We have worked in the renewable energy industry as a researcher, developing sales and markets, along with may inventions and innovations. More Info
Made in USA with Global Energy Millennial Web Engine These pages were made with the Global Energy Web PDF Engine using Filemaker (Claris) software.
Infinity Turbine Developing Spinning Disc Reactor SDR or Spinning Disc Reactors reduce processing time for liquid production of Silver Nanoparticles.
| CONTACT TEL: 608-238-6001 Email: greg@infinityturbine.com | RSS | AMP |