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IbD PU Deliverable 3.1 structure, piping, utilities, and by-product processing. PI technology is ideal for rapid market introduction of products since it reduces the number of process development steps. PI strategy is therefore favourable in fine chemical and pharmaceutical sectors where the period between laboratory and marketing phases can be significantly shortened via acceleration of production rates, thereby meeting patents’ lifetime, prior to their expiry (Reay et al., 2013). 1.4 The challenges for process intensification The proliferation of PI in industry has not achieved the level expected back in the 1970s when the PI concept was invented. The challenges in implementing PI include: Perception of risk Most chemical and pharmaceutical companies are still reluctant to implement PI due to the difficulty in assessing the risk of PI holistically. The lack of industrial case studies and hence the data to model their design and operation make it difficult to carry out economic feasibilities of PI. Industrial conglomerates often put profits ahead of innovation, as the latter would involve incalculable risks. Lack of “champions” within the industry To drive an evolution of a process into an intensified one, a very strong champion (be it an individual or organization) must be at the forefront. These PI “champions” are still rather sparse in industry. The IbD® project, funded by the EU Horizon 2020 paves an important step toward encouraging the implementation of PI within industries, becoming a “PI champion” in its own right. Control and monitoring of PI processes One of the obstacles in PI commercialization are the problems in control and monitoring of a PI process due to its enhanced rates of heat and mass transfer. Realizing this crucial technical issue, work is underway in several institutions, as highlighted in a recent review by Nikačević et al. (2012). Control strategies for intensified processes form a core component within the aforementioned IbD® project. 5PDF Image | Solids handling for intensified process technology
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