PDF Publication Title:
Text from PDF Page: 091
IbD PU Deliverable 3.1 In addition, the foams coat the particles, rather than soaking/wetting them like sprayed liquid, which enables consistent binder distribution. This technique effectively removes the spray nozzle assembly, which eliminates the related clogging problem. Among other advantages include: shorter processing times, suitability for moisture-sensitive formulations, and the usefulness for high potent/low dose drug formulations due to the excellent drug distribution. However, due to its relatively novel method compared to others, further studies are required (Keary and Sheskey, 2004; Koo et al., 2012; Tan et al., 2013). Twin screw granulator (TSG) Twin screw granulator (TSG) is an important recent development in continuous wet granulation, especially in the pharmaceutical industry (an example is shown in Figure 78). Compared to other wet granulation methods, it offers equipment design flexibility, short residence times, wide range of throughput, and an excellent mixing of the formulations. It has also been proven to be a viable alternative to the high shear, fluidized bed granulation, which process is currently challenging. Another plus point is that similar equipment can be used to scale up batch granulation e.g. batch size can be increased by simply operating the machine in longer time. This eliminates scaling-up hurdles (Michaels et al., 2009; Dhenge et al., 2010; El Hagrasy et al., 2013). In other wet granulation equipment, the granulation rate processes i.e. wetting/nucleation, consolidation/growth, and breakage/attrition occur simultaneously. This complicates the control of granule properties as well as the scale-up efforts. TSG in contrast, offers “regime- separated” granulation – thereby, providing a greater opportunity for controlling granule properties e.g. size and density (Emady et al., 2011). It is obvious that TSG offers great enhancements in the wet granulation process. Recent research efforts such as by Vercruysse et al. (2015) and Fonteyne et al. (2015) have shown general positive results from laboratory tests. These indicate the huge potentials for industrial implementation. 83PDF Image | Solids handling for intensified process technology
PDF Search Title:
Solids handling for intensified process technologyOriginal File Name Searched:
solids-handling-sdr.pdfDIY PDF Search: Google It | Yahoo | Bing
Turbine and System Plans CAD CAM: Special for this month, any plans are $10,000 for complete Cad/Cam blueprints. License is for one build. Try before you buy a production license. More Info
Waste Heat Power Technology: Organic Rankine Cycle uses waste heat to make electricity, shaft horsepower and cooling. More Info
All Turbine and System Products: Infinity Turbine ORD systems, turbine generator sets, build plans and more to use your waste heat from 30C to 100C. More Info
CO2 Phase Change Demonstrator: CO2 goes supercritical at 30 C. This is a experimental platform which you can use to demonstrate phase change with low heat. Includes integration area for small CO2 turbine, static generator, and more. This can also be used for a GTL Gas to Liquids experimental platform. More Info
Introducing the Infinity Turbine Products Infinity Turbine develops and builds systems for making power from waste heat. It also is working on innovative strategies for storing, making, and deploying energy. More Info
Need Strategy? Use our Consulting and analyst services Infinity Turbine LLC is pleased to announce its consulting and analyst services. We have worked in the renewable energy industry as a researcher, developing sales and markets, along with may inventions and innovations. More Info
Made in USA with Global Energy Millennial Web Engine These pages were made with the Global Energy Web PDF Engine using Filemaker (Claris) software.
Infinity Turbine Developing Spinning Disc Reactor SDR or Spinning Disc Reactors reduce processing time for liquid production of Silver Nanoparticles.
| CONTACT TEL: 608-238-6001 Email: greg@infinityturbine.com | RSS | AMP |