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IbD PU Deliverable 3.1 Several of the case studies involve slurry flows where there may be opportunities for prior liquid removal. Milling features in three case studies, and the accurate separation of particles into specific size ranges is important. Mixing is common to four of the case studies. Different types of dryers are employed by the companies, ranging from horizontal moving bed dryers to spray and fluid bed dryers. In one case, the spray and fluid bed dryer are within the same unit. Granulation which affects the integrity of the particles produced upstream of the process is also a prominent operation in the case studies. The most promising PI options for the most frequently encountered unit operations involved in the case studies are highlighted in Table 4. Note that these recommendations are based on the documented characteristics of the technologies studied (as highlighted in the review and summarised in Table 2) and they do not necessarily indicate that such processes have already been tested in the technologies in question. Table 4. Suggested PI technologies for selected unit operations Unit operation Milling (Wet milling) Granulation/Particle coating Drying Promising PI options (1) Mechanically agitated: IS (2) Others: WSMM Rotating technologies: Vortex reactor, TORBED reactor, Taylor-Couette (1) Rotating technologies: Vortex, TORBED (2) Electromagnetic fields: Microwaves Mixing (1) Rotating technologies: SD, SCR, RPB, RFB, Taylor-Couette, Vortex, TORBED (2) Mechanically agitated technologies: Coflore technologies, OBR, IS (3) Electromagnetic fields: Ultrasound A strong feature of PI is the ability to combine unit operations to reduce equipment/plant volume. There may be opportunities for combining mixing with other unit operations such as granulation and drying in a multifunctional unit such as a rotating fluidised bed dryer. 95PDF Image | Solids handling for intensified process technology
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