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resources. Another role of colonic microbes is synthesizing vitamins and helping in the absorption of calcium, magnesium, and iron (Roberfroid and others 1995; Miyazawa and others 1996; Younes and others 2001) Trophic activities: An important trophic effect is controlling epithelial cell proliferation and differentiation. All three major short-chain fatty acids stimulate epithelial cell proliferation and differentiation in the large and small intestine (Franke and others 1994). Interactions between gut bacteria and host immunity are another trophic activity. The intestinal mucosa is the man interface between the immune system and the external environment. The interaction between host and bacteria at the mucosal interface plays an important role in development of a competent immune system (Guarner and Malagelada 2003). Protective activities: Intestinal bacteria are important in that they prevent species that are harmful to the host from colonizing the host and they protect against invasion by external microbes which is called barrier effect (Guarner and Malagelada 2003). 2.4.2 Types of intestinal bacteria Not all microbial species in the gut have been identified because of the difficulty of identification. The genera of intestinal bacteria include, Bifidobacterium, Clostridium, Eubacterium, Peptococcus, Peptostreptococcus, and Ruminococcus, which are the predominant ones in humans. Also, there are sub-dominant genera, such as Escherichia, Enterobacter, Enterococcus, Klebsiella, Lactobacillus, Proteus, and others. (Simon and Gorbach 1984; Salminen and others 1998). 17PDF Image | ZINC OXIDE AND SILVER NANOPARTICLES ON INTESTINAL BACTERIA
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